Akili

Akili

Mental Health & Digital Therapeutics

About Akili

Akili Interactive is pioneering a new class of digital medicines that combine world-class neuroscience with video game technology to treat cognitive impairments. The company has developed proprietary technology platforms that deliver specific sensory stimuli and motor challenges designed to target neural systems in the brain related to attentional control. Their flagship product, EndeavorRx, is the first and only FDA-approved prescription video game treatment for children aged 8-17 with primarily inattentive or combined-type ADHD. Building on this technology, Akili launched EndeavorOTC, an over-the-counter treatment for adults with ADHD available without prescription. Both products are built on the company's patented Selective Stimulus Management Engine (SSME) technology, which uses adaptive algorithms to personalize treatment difficulty for each individual patient. The technology has been rigorously evaluated across more than 30 clinical trials, including the STARS-ADHD study published in The Lancet Digital Health. Akili's approach represents a fundamental shift in how medicine is designed, delivered, and experienced—creating treatments that are not just effective, but engaging and enjoyable. The company continues to research applications of their technology across multiple cognitive conditions beyond ADHD, including autism spectrum disorder and sensory processing dysfunction.

Mission & Story

Mission

We believe effective medicine can also be fun and engaging. We're creating a new class of digital medicines for people living with cognitive impairments, delivered through captivating video game experiences.

Founding Story

Developed through the collaboration of world-renowned cognitive neuroscientists and acclaimed entertainment and technology designers to create an entirely new category of medicine built on extensive peer-reviewed research.

Clinical Focus

Medical conditions and clinical areas addressed by Akili.

ADHD (children and adults)Autism Spectrum Disorder with co-occurring ADHD symptomsSensory Processing DysfunctionCOVID Brain FogGeneral cognitive impairments

Who It Serves

Consumers (patients/families)Healthcare providers (prescribers)Payers

Milestones & Awards

Recent Milestones

Launch of EndeavorOTC for adults with ADHD (over-the-counter, available on App Store and Google Play); FDA authorization for EndeavorRx as first prescription video game treatment; CE Mark certification in Europe; Publication of STARS-ADHD trial in The Lancet Digital Health; 2023 ADHD in Workplace Report

Awards & Recognition

First FDA-approved prescription video game treatment; First-of-its-kind over-the-counter digital treatment for adult ADHD

Company Details

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Security & Compliance

FDA AuthorizationCE Mark
Last updated Jun 28, 2026

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