About Avenda Health
Avenda Health is a precision medicine company focused on transforming prostate cancer care through artificial intelligence. The company's flagship product, Unfold AI, is an FDA-cleared platform that generates detailed 3D Cancer Estimation Maps (CEMs) to visualize the precise location and extent of prostate cancer within the prostate gland. By analyzing standard-of-care patient data including MRI scans, fusion biopsy results, pathology reports, and PSA levels, Unfold AI significantly outperforms traditional MRI in identifying where cancer resides. Clinical studies demonstrate that physicians using Unfold AI achieve 84% accuracy in identifying cancer extent, and patients treated with Unfold AI margins are 71% more likely to be cancer-free. The platform addresses a critical gap in prostate cancer treatment: without precise cancer mapping, whole-gland treatments lead to urinary and sexual dysfunction in over 50% of patients, while focal therapy without AI guidance leaves 24-49% of patients with residual cancer. Unfold AI supports multiple treatment modalities including active surveillance, prostatectomy, focal therapy, and radiotherapy by providing actionable insights for surgical planning, biopsy guidance, and treatment targeting. The technology is based on over 100,000 patient data points gathered over 10 years of research and validated in multiple peer-reviewed clinical studies. Avenda Health serves urologists, radiation oncologists, and healthcare systems across the United States, working to make precision-guided prostate cancer care accessible to patients nationwide.
Mission & Story
Mission
Patients should not have to choose between treating their prostate cancer and maintaining their quality of life
Founding Story
Co-founded by CEO Shyam Natarajan, PhD, who has been featured in interviews discussing the company's mission to redefine prostate cancer care
Clinical Focus
Medical conditions and clinical areas addressed by Avenda Health.
Who It Serves
Milestones & Awards
Recent Milestones
CMS established national payment for Unfold AI (July 2024); Partnership with EDAP for world's first AI-assisted Focal One® Robotic HIFU procedures (September 2024); Won Top Digital Health Award at HLTH conference (October 2025); Multiple clinical study publications in 2024-2025
Awards & Recognition
Top Digital Health Award at HLTH 2025; CMS national payment establishment (July 2024)
Key Partnerships
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