About Sempre Health
Sempre Health is a healthcare technology company that has pioneered behavior-based dynamic pricing for prescription medications. The company operates a two-sided marketplace that aligns pharmaceutical manufacturers, health plans, and patients around medication affordability and adherence. Through its SMS-based platform, Sempre engages patients with timely refill reminders and progressively lower copays as they consistently refill their medications on time. The platform requires no app downloads or passwords, making it accessible to patients across all demographics. Sempre partners with health plans to deliver white-labeled adherence interventions at no cost to the plan, with pharmaceutical manufacturers funding the discounts. The company's approach addresses medication nonadherence—a critical challenge in healthcare—by removing cost barriers and using behavioral economics principles to motivate healthy behaviors. Sempre's platform is available at all retail pharmacies across the United States and supports multiple therapeutic areas including diabetes, cardiovascular disease, and respiratory conditions. The company has demonstrated measurable outcomes including 15-25% increases in adherence rates, 45-65% reductions in out-of-pocket costs for enrolled members, and industry-leading Net Promoter Scores above 95. Sempre is backed by leading healthcare and technology investors and maintains HITRUST certification for data security.
Clinical Focus
Medical conditions and clinical areas addressed by Sempre Health.
Who It Serves
Milestones & Awards
Recent Milestones
Prime Therapeutics expanded partnership nationwide in October 2025 after successful pilot. Blue Shield of California presented positive research results at AMCP in April 2024. Dr. John M. O'Brien joined Board of Directors in October 2025. Regence partnership announced June 2026.
Awards & Recognition
Honored by Modern Healthcare in January 2026 for delivering critical intervention in medication affordability crisis
Key Partnerships
Social & Media
Latest Updates

HTN Podcast: Rethinking medication affordability with a two-sided marketplace

Prime Therapeutics expands Sempre Health partnership to rein in drug costs

Sempre Health Honored by Modern Healthcare for Delivering Critical Intervention in the Medication Affordability Crisis

Building and Scaling a Platform Business in Healthcare

Prime Therapeutics and Sempre Health Expand Innovative Behavior-Based Pricing Model to Advance Patient Affordability
Company Details
- Employees
- 11-50
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