Breast implant-associated squamous cell carcinoma (BIA-SCC): Clinicopathologic analysis of two cases with radiologic-pathologic correlation and a review of the literature.

Anna-Lee Clarke-Brodber¹, Pei-Ling Chen², Abid Ulhaque³, Marilin Rosa⁴, Carlos Arturo Cano Munoz⁵

¹Department of Pathology, H. Lee Moffitt Cancer Center, Tampa, FL, USA. Electronic address: Anna-Lee.Clarke@moffitt.org.

²Department of Pathology, H. Lee Moffitt Cancer Center, Tampa, FL, USA.

³Department of Breast Imaging, H. Lee Moffitt Cancer Center, Tampa, FL, USA.

⁴Department of Pathology, NeoGenomics, Fort Myers, FL, USA.

⁵Department of Pathology, Rutgers University, Newark, NJ, USA.

PubMed DOI

Abstract

Breast implant-associated squamous cell carcinoma (BIA-SCC) is an exceptionally rare and poorly characterized malignancy that arises from the fibrous capsule surrounding breast implants. Due to its rarity, the clinicopathologic features and optimal diagnostic strategies remain incompletely defined. This report presents two cases of BIA-SCC, correlating clinical, radiologic, cytologic, pathologic,…

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