Peer-Reviewed Publication
Expert Rev Vaccines2026;25(1):2724614.December 1, 2026Journal Article

Narrative review of the clinical safety of MenACYW-TT: a quadrivalent meningococcal vaccine conjugated to tetanus toxoid licensed in the US and abroad.

Olga Syrkina1, Mary Bausch-Jurken2, Arlette Delgado3, Jelena Jovanovic4, Corwin A Robertson5
1Patient Safety and Pharmacovigilance - Vaccines, Sanofi, Cambridge, MA, USA.
2North America Medical Affairs - Vaccines, Sanofi, Morristown, NJ, USA.
3Patient Safety and Pharmacovigilance - Vaccines, IQVIA, Madrid, Spain.
4Patient Safety and Pharmacovigilance - Vaccines, IQVIA, Belgrade, Serbia.
5Global Medical Affairs - Vaccines, Sanofi, Morristown, NJ, USA.

Abstract

INTRODUCTION: Routine meningococcal vaccination campaigns have substantially reduced the burden of invasive meningococcal disease in pediatric individuals, leading to relative increases in burden in older age groups. There is a need for safe, effective meningococcal vaccines that can be used across broad age ranges. MenACYW-TT, a quadrivalent tetanus-toxoid-conjugate meningococcal vaccine indicate…

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