Design of Chiral Antimony Catalyst for Ring-Opening Reaction of Epoxides with Anilines.

Yan Li¹, Jian Zhang¹, Yi-Fei Zhu², Cheng Wang², Shao-Hua Xiang³, Xiao-Wei Li¹, Jing Guo², Bin Tan¹

¹Shenzhen Grubbs Institute, Department of Chemistry, Southern University of Science and Technology, Shenzhen518055, China.

²XtalPi Inc. (Shenzhen Jingtai Technology Co., Ltd.) , Shenzhen518100, China.

³Advanced Institute for Ocean Research, Southern University of Science and Technology, Shenzhen518055, China.

PubMed DOI

Abstract

Pnictogen-bonding catalysis has emerged as a promising tool for noncovalent transformations; however, its application in asymmetric catalysis remains in its infancy, largely due to the scarcity of efficient chiral catalysts and activating modes. Herein, we report a new class of chiral antimony catalysts featuring strong σ-hole strength and a tunable chiral environment, which are readily assembled…

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