Divergent avian strains drive an off-season influenza A peak in municipal wastewater.

Alexander L Jaffe¹, Alessandro Zulli¹, Dorothea Duong², Bridgette Shelden², Miriam Goldman², Miles Richardson², Marlene K Wolfe³, Alexandria B Boehm¹

¹Department of Civil and Environmental Engineering, Stanford University, Stanford, California, USA.

²Verily Life Sciences, South San Francisco, California, USA.

³Gangarosa Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA.

PubMed DOI

Abstract

Wastewater sequencing is an increasingly valuable tool in tracking the spread of infectious disease agents across space and time in areas of dense human settlement. Among pathogens that can be readily detected by this approach is influenza A, which follows predictable patterns of prevalence through the winter months in North America. Here, we leverage routine surveillance of a municipal wastewater…

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