Peer-Reviewed Publication
J Med Econ2026;29(1):2295-2309.December 1, 2026Journal Article

Cost-effectiveness analysis of elranatamab versus physician's choice of treatment (non-BCMA-directed regimens) in patients with triple class exposed multiple myeloma in Japan.

Akira Yuasa1, Mitsuhiro Nagano1, Yoichi Kamei2, Kengo Hatsuyama3, Hiroyuki Matsuda3, Patrick Hlavacek4, Marco DiBonaventura4, Kenshi Suzuki5
1Japan Access & Value, Pfizer Japan Inc, Tokyo, Japan.
2Pfizer R&D Japan G.K, Tokyo, Japan.
3Real World Evidence Solutions & HEOR, IQVIA Solutions Japan G.K, Tokyo, Japan.
4HTA, Value & Evidence, Pfizer Inc, New York, NY, USA.
5Myeloma/AL Amyloid Unit, Japanese Red Cross Medical Center, Tokyo, Japan.

Abstract

AIM: To evaluate the cost-effectiveness of elranatamab versus physician's choice of treatment (PCT) for patients with triple class exposed multiple myeloma in Japan. MATERIALS AND METHODS: A cost-effectiveness analysis was conducted comparing elranatamab with PCT using a partitioned survival model with three health states from the Japanese public healthcare payer perspective. A weekly cycle lengt…

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