Amebic Liver Abscess Hospitalizations in the United States: A Nationwide Analysis of Trends and Severe Morbidity, 2002-2023.

Akram Alnounou¹, Brian Nohomovich², Mohammad Alabbas³, Kirsten Hickok⁴, Eric Martin Sieloff⁵, Syed-Mohammed Jafri⁶, Serge Sorser⁷, Thomas A Melgar⁸

¹Department of Internal Medicine, Western Michigan University Homer Stryker M.D. School of Medicine, 1000 Oakland Drive, Kalamazoo, MI 49008, USA. Electronic address: akram.alnounou@wmed.edu.

²Department of Gastroenterology, Michigan State University College of Human Medicine/Henry Ford Health Systems Providence, 16001 W Nine Mile Rd, Southfield, MI 48075, USA. Electronic address: bnohomo1@hfhs.org.

³Department of Gastroenterology, Hepatology and Nutrition, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA. Electronic address: alabbam@ccf.org.

⁴Department of Biomedical Informatics, Western Michigan University Homer Stryker M.D. School of Medicine, 1000 Oakland Drive, Kalamazoo, MI 49008, USA. Electronic address: kirsten.hickok@wmed.edu.

⁵Department of Internal Medicine, Western Michigan University Homer Stryker M.D. School of Medicine, 1000 Oakland Drive, Kalamazoo, MI 49008, USA; Division of Gastroenterology, Bronson Methodist Hospital, 601 John St, Kalamazoo, MI 49007, USA. Electronic address: sielofer@bronsonhg.org.

⁶Department of Gastroenterology and Hepatology, Henry Ford Health System, 2799 W Grand Blvd, Detroit, MI 48202, USA. Electronic address: sjafri3@hfhs.org.

⁷Department of Gastroenterology, Michigan State University College of Human Medicine/Henry Ford Health Systems Providence, 16001 W Nine Mile Rd, Southfield, MI 48075, USA. Electronic address: ssorser@gmail.com.

⁸Department of Internal Medicine, Western Michigan University Homer Stryker M.D. School of Medicine, 1000 Oakland Drive, Kalamazoo, MI 49008, USA. Electronic address: thomas.melgar@wmed.edu.

PubMed DOI

Abstract

AIMS: US population-based data on amebic liver abscess (ALA) are limited and predate the ICD-10-CM era. We quantified national trends, inpatient outcomes, and factors associated with severe in-hospital morbidity among adult ALA hospitalizations. METHODS AND RESULTS: We performed a retrospective cross-sectional analysis of the 2002-2023 National Inpatient Sample, excluding 2015. ALA was identified…

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