Peer-Reviewed Publication
J Med Econ2026;29(1):2339-2349.December 1, 2026Journal Article

Retrospective database analysis of annual direct costs and complications for patients with type 1 diabetes and hypoglycemia in the US.

Adriana Boateng-Kuffour1, Nanxin Li1, Vamshi Ruthwik Anupindi2, Keval Chandarana1, Liang Chen1, Michael Hull2, Xiaoyu Zhou2, Jason L Gaglia3, Mitch Dekoven2, Beth Barber1
1Vertex Pharmaceuticals Incorporated, Boston, MA, USA.
2Real World Solutions, IQVIA, Falls Church, VA, USA.
3Joslin Diabetes Center, Harvard Medical School, Boston, MA, USA.

Abstract

BACKGROUND: Type 1 diabetes and hypoglycemia impose substantial clinical and economic burden on patients and healthcare systems. This study examined T1D-related complications and direct costs in people with T1D (pwT1D) and in a subgroup with hypoglycemia in the US. METHODS: IQVIA's PharMetrics Plus database was used to identify adults (≥18 years) with an ICD-10-CM code for T1D between April 1, 20…

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