Health AI Central
Peer-Reviewed Publication
iScience2026;29(9):117436.September 18, 2026Journal Article

An auditory "low road" for threat processing in humans sensitive to fast temporal cues.

Martina T Cinca-Tomás1,2, Emmanouela Kosteletou-Kassotaki1,2, Jordi Costa-Faidella1,2,3, Carles Escera1,2,3, Judith Domínguez-Borràs1,2
1Brainlab-Cognitive Neuroscience Research Group, Department of Clinical Psychology and Psychobiology, University of Barcelona, 08035 Barcelona, Spain.
2Institute of Neurosciences, University of Barcelona, 08035 Barcelona, Spain.
3Institut de Recerca Sant Joan de Déu (IRSJD), 08950 Esplugues de Llobregat, Spain.
PubMed PMC DOI PDF

Abstract

Rapid threat processing is a fundamental and evolutionarily conserved function of the brain. In vision, influential models of emotion propose the existence of a fast subcortical pathway for threat processing, connecting the visual thalamus with the amygdala, driven by coarse visual inputs. In audition, whether such a "shortcut" operates in humans has remained unknown. Here, using psychophysiology…

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