Peer-Reviewed Publication
AIDS Patient Care STDS2026;10872914261486529.September 15, 2026Journal Article

Postpartum Virologic Failure Among Women with HIV Suppressed at Delivery in Spain: Incidence, Timing, and Associated Factors.

Rebeca Izquierdo1,2, Marta Rava1,2, Victoria Hernando1,2, Inés Suárez-García2,3,4, Félix Gutiérrez2,5,6,7, Antonio Rivero2,8,9, Roberto Güerri-Fernández2,10,11, Rafael Rubio2,12,13, Juan García-Arriaza2,14, Manuel Gutiérrez-Cuadra2,15, Laura Pérez-Martínez16, Rosario Palacios17, María José Galindo18, Inmaculada Jarrín1,2,
1CoRIS Cohort Coordination Unit, National Center for Epidemiology, Carlos III Health Institute, Madrid, Spain.
2CIBERINFEC, Carlos III Health Institute, Madrid, Spain.
3Infectious Diseases Group, Department of Internal Medicine, Infanta Sofía University Hospital, Foundation for Biomedical Research and Innovation of Infanta Sofía and Henares University Hospitals (FIIB HUIS HHEN), Madrid, Spain.
4Department of Medicine, Faculty of Medicine, Health and Sports, Universidad Europea de Madrid, Madrid, Spain.
5Department of Internal Medicine, Elche General University Hospital, Elche, Spain.
6Foundation for the Promotion of Health and Biomedical Research of the Valencian Community (FISABIO), Valencia, Spain.
7Faculty of Medicine, Miguel Hernández University, Alicante, Spain.
8Infectious Diseases Unit, Reina Sofía University Hospital, Maimonides Biomedical Research Institute of Cordoba (IMIBIC), Córdoba, Spain.
9Department of Medicine, Faculty of Medicine and Nursing, University of Córdoba, Córdoba, Spain.
10HIV-STD Division, Department of Internal Medicine, Group for Research in Viral Infections (GRIV), Hospital del Mar Research Institute, Barcelona, Spain.
11Department of Medicine and Life Sciences (MELIS), Pompeu Fabra University, Barcelona, Spain.
12HIV Unit, Department of Internal Medicine, 12 de Octubre University Hospital, Health Research Institute Hospital 12 de Octubre (imas12), Madrid, Spain.
13Department of Medicine, Complutense University of Madrid, Madrid, Spain.
14Department of Molecular and Cellular Biology, National Center for Biotechnology (CNB), Spanish National Research Council (CSIC), Madrid, Spain.
15Department of Infectious Diseases, Marqués de Valdecilla University Hospital-IDIVAL, Santander, Spain.
16Department of Infectious Diseases, San Pedro University Hospital, Logroño, Spain.
17Infectious Diseases Unit, Virgen de la Victoria University Hospital-IBIMA Plataforma BIONAND, Málaga, Spain.
18Infectious Diseases Unit, Valencia University Clinical Hospital, Valencia, Spain.

Abstract

The postpartum period remains a vulnerable phase for maintaining virologic suppression among women with HIV (WWH); however, evidence on postpartum virologic failure (VF) among women virologically suppressed at delivery is limited. We analyzed data from the CoRIS cohort including WWH aged 18-50 years who had a live birth while receiving antiretroviral therapy (ART) and were virologically suppressed…

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