Peer-Reviewed Publication
World Psychiatry2026;25(3):359-381.October 1, 2026Journal Article

The lived experience of trans persons: a bottom-up review co-written by experts by experience and academics.

Paolo Fusar-Poli1,2,3,4, Andrés Estradé1, René Rosfort5, Annemijn van der Schaar6, Jordan Searle-Barnes7, Matthew Jackman8, Parth Sharma9, Aqsa Shaikh10, Vanessa Lacey11, Sameera M Jahagirdar12, Anu Savio Thelly13, Giovanni Stanghellini14,15, Cecilia Maria Esposito16, Milena Mancini17, Ilaria Bonoldi1, Stefano Damiani2, Elisa Figazzolo1,2, Giorgia Torta2, Andrea De Micheli1,3, Laura Fusar-Poli2,18, Ilaria Basadonne2, Samuele Cortese19,20,21,22,23, Dong Keon Yon24, Giovanni Castellini25, Mario Maj26
1Early Psychosis: Interventions and Clinical-detection (EPIC) Lab, Department of Psychosis Studies, King's College London, London, UK.
2Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy.
3OASIS Service, South London and Maudsley NHS Foundation Trust, London, UK.
4Department of Psychiatry and Psychotherapy, University Hospital, Ludwig-Maximilian-University, Munich, Germany.
5S. Kierkegaard Research Centre, University of Copenhagen, Copenhagen, Denmark.
6University of Humanistic Studies, Utrecht, The Netherlands.
7Department of Social Sciences, University of Glasgow, Glasgow, UK.
8Centre for Disability Research and Policy, University of Sydney, Sydney, NSW, Australia.
9Sangath India, Goa, India.
10Hamdard Institute of Medical Sciences and Research, New Delhi, India.
11Gendercare Ireland, Waterford, Ireland.
12West Middlesex University Hospital, Chelsea and Westminster NHS Trust, London, UK.
13Department of Palliative Medicine, Mahatma Gandhi Medical College and Research Institute, Sri Balaji Vidyapeeth, Puducherry, India.
14Department of Health Sciences, University of Florence, Florence, Italy.
15D. Portales University, Santiago, Chile.
16Department of Neurosciences and Mental Health, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
17Department of Psychology, University of Chieti and Pescara "G. d'Annunzio", Chieti, Italy.
18IRCCS Maugeri, Pavia, Italy.
19Developmental EPI (Evidence synthesis, Prediction, Implementation) Lab, Centre for Innovation in Mental Health, School of Psychology, Faculty of Environmental and Life Sciences, University of Southampton, Southampton, UK.
20Clinical and Experimental Sciences (CNS and Psychiatry), Faculty of Medicine, University of Southampton, Southampton, UK.
21Hampshire and Isle of Wight Healthcare NHS Foundation Trust, Southampton, UK.
22Hassenfeld Children's Hospital at NYU Langone, New York University Child Study Center, New York City, NY, USA.
23Department of Precision and Regenerative Medicine - Jonic Area, University of Bari "Aldo Moro", Bari, Italy.
24Department of Pediatrics, Kyung Hee University College of Medicine, Seoul, South Korea.
25Psychiatric Unit, Department of Health Sciences, University of Florence, Florence, Italy.
26Department of Psychiatry, University of Campania "L. Vanvitelli", Naples, Italy.

Abstract

We present here the first bottom-up review of the lived experience of trans persons, co-written by experts by experience and academics. We sourced the medical and non-medical literature, focusing on first-person narratives, and critically extracted experiential themes, which were reviewed and appraised in collaborative workshops and eventually shared through a cloud-based system. Numerous experts…

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