Peer-Reviewed Publication
Phys Med Biol2026September 15, 2026Journal Article

NHPVS: a nodule-aware deep learning method for high-abundance pulmonary vessel segmentation on chest CT.

Rui Zhao1, Shaoze Luo2, Longfei Zhao2, Bing Li3, Zhuangfei Ma2, Ruijie Zhao1, Jiaru Wang1, Ran Xiao1, Sirong Piao1, Ying Ming1, Zicheng Liao1, Qiqi Xu4, Wei Song5
1Radiology, Peking Union Medical College Hospital, No.1 Shuaifuyuan Wangfujing Dongcheng District, Beijing, 100730, China, Beijing, Beijing, 100730, China.
2Research and Development Center, Canon Medical Systems China Co Ltd, 23rd Floor, Tower A, Ping An International Financial Center No.3, Xinyuan South Road, Chaoyang District, Beijing 100027, China, Beijing, Beijing, 100027, China.
3Research and Development Center, Canon Medical Systems China Co Ltd, 23rd Floor, Tower A, Ping An International Financial Center No.3, Xinyuan South Road, Chaoyang District, Beijing, 100027, China, Beijing, Beijing, 100027, China.
4Research and Development Center, Canon Medical Systems China Co Ltd, 23rd Floor, Tower A, Ping An International Financial Center No.3, Xinyuan South Road, Chaoyang District, Beijing, 100027, China, Beijing, 100027, China.
5Radiology, Peking Union Medical College Hospital, No.1 Shuaifuyuan Wangfujing Dongcheng District, Beijing, 100730, China, Beijing, 100730, China.

Abstract

OBJECTIVE: Deep learning-based segmentation of pulmonary vessels is challenged by vessel-nodule confusion and insufficient detection of small vessels. To address these issues, we propose a Nodule-aware High-abundance Pulmonary Vessel Segmentation (NHPVS) framework that enhances nodule differentiation and improves small vessel segmentation. APPROACH: This multi-center study retrospectively collect…

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