Comparative performance of multiparametric MRI models for preoperative diagnosis of macrotrabecular-massive hepatocellular carcinoma: A pilot study of DWI, IVIM, and fractional order calculus techniques.

Furong Wan¹, Wenjian Wang¹, Jiale Hang¹, Zhaorong Wang¹, Yingying Peng¹, Jun Sun¹, Shaofeng Duan², Martin Prince³, Jing Ye¹, Xianfu Luo⁴

¹Department of Radiology, Northern Jiangsu People's Hospital, Northern Jiangsu People's Hospital Affiliated to Yangzhou University, Yangzhou 225001, China.

²Department of Collaborative Innovation, Shanghai United Imaging Healthcare Co., Ltd., Shanghai 201807, China.

³Department of Radiology, Weill Medical College of Cornell University, New York 10065, USA.

⁴Department of Radiology, Northern Jiangsu People's Hospital, Northern Jiangsu People's Hospital Affiliated to Yangzhou University, Yangzhou 225001, China. Electronic address: xianfu-luo@hotmail.com.

PubMed DOI

Abstract

OBJECTIVES: To explore the feasibility of diffusion-weighted imaging (DWI), intravoxel incoherent motion (IVIM), and fractional order calculus (FROC) models in preoperatively predicting macrotrabecular-massive subtype of hepatocellular carcinoma (MTM-HCC). MATERIALS AND METHODS: 101 pathologically confirmed HCC patients underwent multi-b-value DWI. Diffusion parameters including apparent diffusio…

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