Ambient air pollutant mixtures in relation to sonographic endometrial receptivity parameters during the peri-implantation window: a clinic-based observational study.

Heze Xu¹, Zhijiao Wang¹, Huixin Zhan², Yijia Liu¹, Shanwei Xing¹, Zekai Bai¹, Jingshuang Zhou¹, Hang Zhen¹, Jiapo Li¹, Chong Qiao³

¹Department of Obstetrics and Gynecology, Shengjing Hospital, China Medical University, Shenyang, Liaoning Province, China; Key Laboratory of Maternal-Fetal Medicine of Liaoning Province, Shenyang, Liaoning, China; Research Center of China Medical University Birth Cohort, Shenyang, Liaoning Province, China.

²Department of computational biomedicine, cedars sinai medical center, Los Angeles, CA, USA.

³Department of Obstetrics and Gynecology, Shengjing Hospital, China Medical University, Shenyang, Liaoning Province, China; Key Laboratory of Maternal-Fetal Medicine of Liaoning Province, Shenyang, Liaoning, China; Research Center of China Medical University Birth Cohort, Shenyang, Liaoning Province, China. Electronic address: qiaochong2002@hotmail.com.

PubMed DOI

Abstract

Although air pollution has been linked to adverse reproductive outcomes, its direct effect on endometrial receptivity-a critical factor for embryo implantation-remains unclear at the population level. This study aimed to evaluate the associations of exposure to a mixture of six ambient air pollutants (PM2.5, PM10, CO, NO2, SO2, O3) with sonographic endometrial receptivity parameters (thickness and…

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