Health AI Central
Peer-Reviewed Publication
Geroscience2026September 15, 2026Journal Article

Common and distinct plasma proteomic signature of aerobic and motor physical activity interventions and their link to episodic memory.

Pauline Mury1, Katia Jaulgey2, Tudor Vrinceanu2, Kristell Pothier3, Nicolas Berryman4,5, Brittany Intzandt6, Maxime Lussier7, Thien-Tuong Minh Vu8, Anil Nigam2,9, Laurent Bosquet10, Antony D Karelis4,7, Karen Z H Li11,12, Louis Bherer2,7,9
1Research Centre and Centre EPIC, Montreal Heart Institute, Montreal, QC, Canada. pauline.mury@umontreal.ca.
2Research Centre and Centre EPIC, Montreal Heart Institute, Montreal, QC, Canada.
3Department of Psychology, PAVeA Laboratory (UR 2114), University of Tours, Tours, France.
4Department of Physical Activity Sciences, University of Quebec at Montreal, Montreal, Quebec, Canada.
5National Institute of Sport of Quebec, Montreal, Quebec, Canada.
6Kinesiology & Health Science, Faculty of Health, York University, Toronto, ON, M3J 1P3, Canada.
7Research Center of the Institute of Geriatrics of Montreal, Montreal, QC, Canada.
8Research Centre, University of Montreal Hospital Centre, Montreal, QC, Canada.
9Department of Medicine, University of Montreal, Montreal, QC, Canada.
10Laboratory MOVE (UR 20296), Faculty of Sport Sciences (UFR STAPS), University of Poitiers, Poitiers, France.
11PERFORM Centre, Concordia University, Montréal, QC, Canada.
12Department of Psychology, Concordia University, Montreal, QC, Canada.
PubMed DOI

Abstract

Aging is accompanied by chronic low-grade inflammation which has been associated with cognitive decline. Physical activity might regulate plasma levels of inflammatory-related proteins and may contribute to cognitive benefits, although the underlying mechanisms remain poorly understood. This exploratory secondary analysis aimed to evaluate whether different physical activity modalities were associ…

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