Geneoscopy

Geneoscopy

Precision Medicine & Genomics

About Geneoscopy

Geneoscopy is a precision medicine company focused on transforming gastrointestinal health through innovative molecular diagnostic tests. The company has developed a proprietary stool-derived eukaryotic RNA (seRNA) technology platform that enables noninvasive screening, detection, and monitoring of gastrointestinal diseases. Geneoscopy's flagship product, ColoSense, is the first FDA-approved RNA-based stool test for colorectal cancer screening in adults aged 45 and older. The company's mission is to empower patients and healthcare providers with molecular-based tests that help prevent, detect, and monitor disease. By offering a convenient, at-home collection method, Geneoscopy addresses the significant gap in colorectal cancer screening rates, where over 40% of eligible patients fail to get screened due to the inconvenience and invasive nature of colonoscopies. Beyond colorectal cancer, Geneoscopy is advancing applications of its stool RNA technology to monitor disease activity and predict therapeutic response in inflammatory bowel disease. The company partners with biopharma organizations and research institutions to develop companion diagnostics and clinical trial tools. Geneoscopy's platform-agnostic RNA extraction technology can be evaluated using next-generation sequencing, ddPCR, qPCR, molecular barcoding, or microarray technology, providing comprehensive insights into the stool-derived transcriptome for various gastrointestinal disease indications.

Mission & Story

Mission

To empower patients and healthcare providers to transform gastrointestinal health with our innovative tests that help prevent, detect, and monitor disease.

Founding Story

Co-founders Andrew Barnell and Dr. Erica Barnell established Geneoscopy with a commitment to bridging the gap in colorectal cancer screening rates. Dr. Erica Barnell completed her MD/PhD at Washington University School of Medicine in Molecular Genetics and Genomics from the McDonnell Genome Institute, where she spearheaded the clinical and regulatory development of ColoSense. Andrew Barnell brought experience from healthcare investment banking at J.P. Morgan and private equity at Lindsay Goldberg.

Clinical Focus

Medical conditions and clinical areas addressed by Geneoscopy.

Colorectal cancerInflammatory bowel diseaseUlcerative colitisCrohn's diseaseHigh-risk adenomasOther gastrointestinal diseases

Who It Serves

Healthcare providersPatientsBioPharma companiesResearch institutions

Milestones & Awards

Recent Milestones

FDA approval of ColoSense as the first RNA-based stool test for colorectal cancer screening. Dr. Erica Barnell completed MD/PhD in 2023. Expansion into inflammatory bowel disease monitoring applications.

Awards & Recognition

Dr. Erica Barnell named to Forbes' 30 Under 30 in 2020

Key Partnerships

BioPharma partnerships for GI disease clinical trialsResearch partnerships for diagnostic development

Company Details

Headquarters
St. Louis, MO, USA

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Security & Compliance

HIPAA
Last updated Jun 29, 2026

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