Quantum-Si

Quantum-Si

Precision Medicine & Genomics

About Quantum-Si

Quantum-Si is pioneering the post-genomic era by making protein sequencing accessible to researchers worldwide. Founded in 2013, the company has developed the world's first next-generation protein sequencing instruments—Platinum and Platinum Pro—which deliver single-molecule, single-amino acid resolution in compact benchtop systems. By integrating biology, chemistry, and artificial intelligence, Quantum-Si empowers researchers to study proteins at an unprecedented scale and detail. The company's proprietary technology uses kinetic signatures to sequence proteins directly at the single-molecule level, providing capabilities that simplify sequencing compared to Edman degradation, dive deeper than mass spectrometry with single-molecule resolution, and detect amino acid-level changes missed by immunoassays. This approach enables precise detection of proteoforms, post-translational modifications, protein variants, and isobaric variations without relying on antibodies or complex workflows. Quantum-Si's platforms support a streamlined workflow requiring less than three hours of hands-on time and work with nanogram protein inputs (200 ng or less). The technology serves diverse applications including biomarker discovery, disease mechanism research, drug development, antibody characterization, and protein barcoding for multiplexed variant screening. The company's innovation is driving groundbreaking advancements in scientific research, therapeutic development, and clinical proteomics, with recent peer-reviewed publications demonstrating value in clinical research and pathogen/toxin detection.

Mission & Story

Mission

Pioneering the post-genomic era by making protein sequencing accessible

Founding Story

Founded in 2013 to pioneer accessible protein sequencing technology

Who It Serves

Academic research labsBiotech companiesPharmaceutical companiesResearch institutions

Milestones & Awards

Recent Milestones

Expansion of Proteus Roadshow (June 2026). Partnership with Cell Signaling Technology for PTM analysis (June 2026). Publication of peer-reviewed paper in Analytical Chemistry from Stanford. Preprint publication from Naval Research Laboratory on pathogen detection.

Awards & Recognition

Next-Generation Protein Sequencing Technology Innovation Leadership 2023. Proteomics Company of the Year. Innovation by Design 2023.

Key Partnerships

Cell Signaling Technology (post-translational modification analysis partnership)NVIDIA (accelerated computing and AI technology)Stanford University (clinical proteomics research)U.S. Naval Research Laboratory (pathogen/toxin detection research)University of Virginia School of Medicine (proteoform research)

Company Details

Founded
2013

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Last updated Jul 1, 2026

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